• Joshua D Horton, MD
  • Jennie Stuart Health
  • BlueCreek South
    10755 Eagle Way, Ste 201
    Hopkinsville, KY 42240
  • (270) 807-5430
  • (270) 887-0915
Joshua D Horton, MD
Otolaryngology (Ear, Nose & Throat), ENT (Ear Nose Throat)
Indiana University – Purdue University Indianapolis (IUPUI), New York University (NYU) Grossman School of Medicine
Medical University of South Carolina Otolaryngology – Head & Neck Surgery
Board Certification
American Board of Otolaryngology – Head & Neck Surgery (eligible)
American Academy of Otolaryngology- Head and Neck Surgery (AAO-HNS)
Doctor Bio

Dr. Horton was born and raised in small rural town in southern Indiana. Growing up he developed a passion for science, the outdoors, and sports. After winning a state championship in baseball his senior year of high school, he went on to attend Indiana University-Purdue University Indianapolis (IUPUI). He majored in biochemistry and graduated with a 4.0 GPA and Highest Distinction. Following this, he obtained his MD at New York University School of Medicine, now ranked the #2 medical school by U.S News and World Report. In addition to his studies, Dr. Horton spent a significant amount of time during medical school conducting high impact scientific research.

Following medical school, he completed his Otolaryngology - Head and Neck Surgery training at the Medical University of South Carolina, one of the top-ranked programs in the country. Also known as Ear, Nose, Throat (ENT), this specialty is one of the most competitive in medicine. During training, Dr. Horton acted as primary surgeon on nearly 3000 procedures, while continuing to participate in medical research and authoring numerous publications.

Dr. Horton’s arrival brings much-needed ENT care to the Christian, Todd, and Trigg county communities. He has a special interest in treating the full breadth of adult and pediatric ENT conditions. He has additional training in minimally invasive balloon sinuplasty and salivary endoscopy. Dr. Horton provides care for the following issues: 


Fly fishing, cooking, time with friends/family, hiking, golfing, playing and watching sports, traveling, non-fiction books.


1. H Knochelmann, J. D. Horton, … C Paulos, D Neskey: Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma. Cancer Cell, under review June 2021.
2. S Liu, H Knochelmann, …, J. D. Horton, … C Paulos, D Neskey, R Lo: Response and Recurrence Correlates in Patients Treated with NeoadjuvantAnti-PD-1 Therapy for Resectable Oral-Cavity Squamous Cell Carcinoma. Cancer Cell, under review June 2021.
3. J. D. Horton, J Davies, V Vaitaitis, T Rist, A Agur, and T. Day: Aberrant hypoglossal nerve during neck dissection. JAMA Otolaryngol Head Neck Surg, ePub June 3, 2021. 
4. J. D. Horton: To Be a Partner in Life-Resident Training During the COVID-19 Pandemic. JAMA Otolaryngol Head Neck Surg, 146(7), 601-602 (2020) doi:10.1001/jamaoto.2020.0921
5. Y. Xiong, D. M. Neskey, J. D. Horton, C. M. Paulos, H. M. Knochelmann, K. E. Armeson and M. R. I. Young: Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma. BMC Cancer, 20(1), 229 (2020) doi:10.1186/s12885-020-06726-3
6. C. Poff, J. D. Horton, R. Boerner, A. P. Marston, S. A. Nguyen and D. R. White: Publishing trends in velopharyngeal insufficiency. Int J Pediatr Otorhinolaryngol, 129, 109761 (2020) doi:10.1016/j.ijporl.2019.109761
7. H. M. Knochelmann, C. J. Dwyer, A. S. Smith, J. S. Bowers, M. M. Wyatt, M. H. Nelson, G. O. Rangel Rivera, J. D. Horton, C. Krieg, K. Armeson, G. B. Lesinski, M. P. Rubinstein, Z. Li and C. M. Paulos: IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors. Cancer Res, 80(18), 3920-3932 (2020) doi:10.1158/0008-5472.Can-19-3685
8. J. D. Horton, C. Corrigan, T. Patel, C. Schaffer, R. A. Cina and D. R. White: Effect of a Standardized Electronic Medical Record Order Set on Opioid Prescribing after Tonsillectomy. Otolaryngol Head Neck Surg, 163(2), 216-220 (2020) doi:10.1177/0194599820911721
9. S. Koochakzadeh, J. R. Dornhoffer, J. D. Horton and T. A. Meyer: Carotid-cochlear dehiscence: a dangerous mimicker of inner ear pathologies. BMJ Case Rep, 12(7) (2019) doi:10.1136/bcr-2019-229773
10. J. D. Horton, D. R. White and R. A. Cina: Response to "Confounding factors for opioid prescription after common pediatric surgeries". J Pediatr Surg, 54(7), 1514 (2019) doi:10.1016/j.jpedsurg.2019.02.024
11. J. D. Horton, S. Munawar, A. Feuvrier, C. Corrigan, M. Lockett, D. White and R. A. Cina: Specialty-specific reduction in opioid prescribing after common pediatric surgical operations. J Pediatr Surg, 54(10), 1984-1987 (2019) doi:10.1016/j.jpedsurg.2019.02.008
12. J. D. Horton, S. Munawar, C. Corrigan, D. White and R. A. Cina: Inconsistent and excessive opioid prescribing after common pediatric surgical operations. J Pediatr Surg, 54(7), 1427-1431 (2019) doi:10.1016/j.jpedsurg.2018.07.002
13. J. D. Horton, H. M. Knochelmann, T. A. Day, C. M. Paulos and D. M. Neskey: Immune Evasion by Head and Neck Cancer: Foundations for Combination Therapy. Trends in Cancer, 5(4), 208-232 (2019) doi:10.1016/j.trecan.2019.02.007
14. J. D. Horton, S. H. Gnagi, C. M. Atwood, S. A. Nguyen and D. R. White: Pharyngeal Flap Versus Sphincter Pharyngoplasty for Velopharyngeal Insufficiency: A Review of the 2014 and 2015 American College of Surgeons National Surgical Quality Improvement Project-Pediatrics Data. J Craniofac Surg, 30(2), 554-556 (2019) doi:10.1097/scs.0000000000005164
15. J. D. Horton, C. Atwood, S. Gnagi, R. Teufel and C. Clemmens: Temporal Trends of Pediatric Dysphagia in Hospitalized Patients. Dysphagia, 33(5), 655-661 (2018) doi:10.1007/s00455-018-9884-9
16. G. Y. Kim, P. F. Lawrence, R. S. Moridzadeh, K. Zimmerman, A. Munoz, K. Luna-Ortiz, G. S. Oderich, J. de Francisco, J. Ospina, S. Huertas, L. R. de Souza, T. C. Bower, S. Farley, H. A. Gelabert, M. R. Kret, E. J. Harris, Jr., G. De Caridi, F. Spinelli, M. R. Smeds, C. D. Liapis, J. Kakisis, A. P. Papapetrou, E. S. Debus, C. A. Behrendt, E. Kleinspehn, J. D. Horton, F. F. Mussa, S. W. K. Cheng, M. D. Morasch, K. Rasheed, M. E. Bennett, J. Bismuth, A. B. Lumsden, C. J. Abularrage and A. Farber: New predictors of complications in carotid body tumor resection. J Vasc Surg, 65(6), 1673-1679 (2017) doi:10.1016/j.jvs.2016.12.124
17. K. Tam, M. Schultz, T. Reyes-Robles, B. Vanwalscappel, J. D. Horton, F. Alonzo, 3rd, B. Wu, N. R. Landau and V. J. Torres: Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5. mBio, 7(6) (2016) doi:10.1128/mBio.02024-16
18. F. F. Mussa, J. D. Horton, R. Moridzadeh, J. Nicholson, S. Trimarchi and K. A. Eagle: Acute Aortic Dissection and Intramural Hematoma: A Systematic Review. JAMA, 316(7), 754-63 (2016) doi:10.1001/jama.2016.10026
19. J. D. Horton, T. Kölbel, S. Haulon, A. Khoynezhad, R. M. Green, M. A. Borger and F. F. Mussa: Endovascular Repair of Type A Aortic Dissection: Current Experience and Technical Considerations. Semin Thorac Cardiovasc Surg, 28(2), 312-317 (2016) doi:10.1053/j.semtcvs.2015.12.004
20. J. D. Horton, D. R. Friedmann and J. T. Roland, Jr.: Delayed Extradural CSF Collection Following Pediatric Cochlear Implantation: Report of Two Cases. Otol Neurotol, 37(6), 654-7 (2016) doi:10.1097/mao.0000000000001035
21. J. D. Horton, E. W. Cerrati and C. Z. Liu: Unilateral Cystic Parotid Lesion in a Middle-Aged Man. JAMA Otolaryngol Head Neck Surg, 142(8), 797-8 (2016) doi:10.1001/jamaoto.2015.3985
22. J. D. Horton, A. A. Arbini, M. A. Perle and B. G. Raphael: Rapid and robust reversion to essential thrombocythemia on treatment with Decitabine in a case of hydroxyurea-induced t-MDS/AML. Clin Case Rep, 4(1), 46-50 (2016) doi:10.1002/ccr3.431
23. J. D. Horton, G. Mittl, M. Thorp and R. Mitnick: The woman without a history. BMJ Case Rep, 2015 (2015) doi:10.1136/bcr-2015-210889
24. F. H. Andrews, J. D. Horton, D. Shin, H. J. Yoon, M. G. Logsdon, A. M. Malik, M. P. Rogers, M. M. Kneen, S. W. Suh and M. J. McLeish: The kinetic characterization and X-ray structure of a putative benzoylformate decarboxylase from M. smegmatis highlights the difficulties in the functional annotation of ThDP-dependent enzymes. Biochim Biophys Acta, 1854(8), 1001-9 (2015) doi:10.1016/j.bbapap.2015.04.027
25. J. D. Horton, E Herlihy, and M Hochman. "Periocular pediatric vascular anomalies," Evidence-based Evaluation and Treatment of Head and Neck Vascular Anomalies. Ed. Jonathon Perkins, 2018.
26. J. D. Horton, D Gupta, and M Hochman. "Capillary malformations," Evidence-based Evaluation and Treatment of Head and Neck Vascular Anomalies. Ed. Jonathon Perkins, 2018.